What is the main issue in Leber's Congenital Amaurosis?

What is the main issue in Leber's Congenital Amaurosis?

• A. Underdevelopment of the optic nerve
• B. Degeneration of the retina
• C. Visual field deficit
• D. Small eye size

Answer: (B)

Leber's Congenital Amaurosis (LCA) is primarily characterized by degeneration of the retina. This condition is a genetic disorder that leads to significant visual impairment or blindness from birth or during early infancy. The degeneration affects the retinal photoreceptors, particularly the rods and cones, which are essential for vision. In LCA, the malfunction or absence of these photoreceptors leads to difficulty in processing visual information, resulting in severe vision loss. This retinal degeneration can be caused by various genetic mutations that impact the structure and function of the retina. Therefore, understanding that the central issue in LCA is related to retinal degeneration is crucial for recognizing the implications for vision and the types of interventions that might be employed in occupational therapy to assist those affected by this condition.

Leber's Congenital Amaurosis (LCA) is primarily characterized by degeneration of the retina. This condition is a genetic disorder that leads to significant visual impairment or blindness from birth or during early infancy. The degeneration affects the retinal photoreceptors, particularly the rods and cones, which are essential for vision.

In LCA, the malfunction or absence of these photoreceptors leads to difficulty in processing visual information, resulting in severe vision loss. This retinal degeneration can be caused by various genetic mutations that impact the structure and function of the retina. Therefore, understanding that the central issue in LCA is related to retinal degeneration is crucial for recognizing the implications for vision and the types of interventions that might be employed in occupational therapy to assist those affected by this condition.